Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity
August 7, 2023 1h 40m 18 chapters
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0:00 Ketamine 5:13 Ketamine & PCP; Clinical & Recreational Use 9:00 Depression & Current Treatments 15:17 Preclinical Models of Depression & Ketamine; “Learned Helplessness” 22:19 Ketamine & Clinical Uses; Depression & Suicidality 28:32 Ketamine & Other Psychiatric Challenges; Relief & Durability 34:29 NMDA Receptor & Neuroplasticity 41:36 Excitatory & Inhibitory Communication, Seizure, NMDA Receptors & Ketamine 48:26 How Ketamine Functions in Brain; Acute & Long-Term Effects 55:42 Brain-Derived Neurotrophic Factor (BDNF) & Ketamine Therapy 1:03:40 Ketamine & Opioid Pathway 1:10:10 Divergent Mechanisms of Immediate & Long-Term Effects 1:15:45 Habenula, Pro-Depressive Behaviors & Ketamine Therapy 1:20:36 Ketamine & Context-Dependent Strategy; Reward Pathway 1:22:45 Dissociative States
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